BURN WOUND HEALING ACTIVITY USING BLACK TURMERIC EXTRACT EMULGEL (Curcuma caesia Roxb) IN WHITE RABBIT ANIMAL MODEL (New Zealand)
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Burns are tissue damage caused by contact with a heat source. Black turmeric (Curcuma caesia Roxb) contains flavonoids, tannins, and alkaloids that function as anti-inflammatory and antibacterial. This study aims to determine the formulation of black turmeric extract emulgel with variations in HPMC concentration (2%, 4%, 6%) that are effective in healing burn wounds. The burn wound healing test was conducted on the backs of New Zealand rabbits for 21 days, and evaluation of the physical quality test of black turmeric extract emulgel which includes organoleptics, viscosity, pH, spreadability, adhesiveness and homogeneity. The results of this study showed that the emulgel had good physical quality and the variation of HPMC emulgel influenced the burn wound healing process. Black turmeric extract emulgel formula with HPMC variation that is most effective in healing burns is black turmeric extract emulgel with 4% HPMC.
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