AKTIVITAS ANTIOKSIDAN SEDIAAN NANOPARTIKEL KITOSAN EKSTRAK ETANOL ROSELA (Hibiscus sabdariffa L.) PADA TIKUS HIPERKOLESTEROL TERHADAP AKTIVITAS ENZIM SOD
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Riesanti D.G, Masdiana C Padagawa, Herawati., 2004, Kadar HDL, Kadar LDL dan Gambaran Histopatologi Aorta Pada Hewan Model Tikus (Rattus Norvegicus) Hiperkolesterolemia Dengan Terapi Ekstrak Air Ambrosil J, C Silva, JC Galofre, J Escalada, S Santos, D Milla, N Vila, P Iban, MJ Gil2, V Valentı, F Rotellar, B Ramı´rez, J Salvador and G Fru¨hbeck., 2012, Body mass index classification misses subjects with increased cardiometabolic risk factors related to elevated adiposity, International Journal of Obesity 36, 286–294.
Anonim., 2004, Ekstrak Tumbuhan Indonesia, Volume 2, Badan Pengawasan Obat dan Makanan Republik Indonesia.
Ariati, R., 2012, Pengaruh fraksi air kelopak bunga rosella (hibiscus sabdariffa l.) Terhadap Kadar Kolesterol Darah Tikus Putih Jantan Hiperkolesterol dan Hiperkolesterol-Disfungsi Hati, Tesis, Universitas Andalas, Padang.
Cartron, E., 2001. Specific antioxidant activity of caffeoyl derivative and other natural phenolic compounds, LDL protection against oxidation and decrease in the proinflammatory lysophosphatidylcholine production. Journal of Natural Products 64, 480–486.
Erusalimsky, JD. Dan Kurz, D.J., 2006, Endhotelial Cell Senescense. In: Moncada, S. Dan Higgs, A, editors. The Vasculer Endhotellium II. Nw York: Springer. P 214-238.
Gaet, N., 1999. Hibiscus sabdariffa L. In: Ivan, A. (Ed.), Medicinal Plants of the World. Human Press, New York, pp. 165–170.
Gupta, V. Karar, P. Ramesh, S. Misra, S. And Gupta, A. 2010. Nanoparticle Formulation for Hydrophilic & Hydrophobic Drugs. Int. J. Res. Pharm. Sci. Vol-1, Issue-2, 163-169.
Hidayati S., 2007, Efek Pemberian Ekstrak Rosela (Hibiscus Sabdariffa L.) Terhadap Kadar LDL-HDL Kolesterol Serum Tikus Strain Wistar Dengan Diet Atherogenik, Jurnal Saintika, Lembaga Penelitian Univsitas Brawijaya Malang, Vol. 13 no. 5.
Hirunpanich V, Anocha Utaipat, Noppawan Phu±mala Morales, Nuntavan Bunyapraphatsara, Hitoshi Sato, Angkana Herunsale, Chuthamanee Suthisisang., 2006, Hypocholesterolemic and antioxidant effects of aqueous extracts from the dried calyx of Hibiscus sabdariffa L. in hypercholesterolemic rats, Journal of Ethnopharmacology 103 (2006) 252–260.
Longo VD, Gralla EB, Valentine JS., 1996, Superoxide dismutase activity is essential for stationary phase survival in Saccharomyces cerevisiae. Mitochondrial production of toxic oxygen species in vivo, J Biol Chem 271: 12275–12280.
Mohanraj and Chen, 2006, Nanoparticles – A Review, Trop J Pharm Res, June 2006; 5 (1) : 561-573.
Pham-Huy, L.A.P., He, H., Pham-Huy, C. 2008. Free Radicals, Antioxidants in Disease and Health. Int J Biomed Sci 4: 89-96.
Ramsdonk J.M.Van, Siegfried Hekimi., 2009, Deletion of the Mitochondrial Superoxide Dismutase sod Extends Lifespan in Caenorhabditis elegans, Department of Biology, McGill University, Canada.
Benalu Mangga, Thesis, Universitas Brawijaya, Malang.
Riski I., 2014, Formulasi Nanopartikel Kitosan Ekstrak Bunga Rosella (Hibiscus Sabdariffa L.) Dan Uji Aktivitas Antioksidan Pada Sel Darah Merah Domba, Tesis, Universitas Ahmad Dahlan, Yogyakarta.
Safitri M., 2014, Aktivitas Antioksidan Sediaan Nanopartikel Kitosan Ekstrak Etanol Rosela (Hibiscus Sabdariffa L.) Pada Tikus Hiperkolesterol Terhadap Profil Lipid, Aktivitas Enzim Katalase dan Ekspresi Gen Katalase, Tesis, Universitas Ahmad Dahlan.
Suwandi, T., 2012, Pemberian Ekstrak Kelopak Bunga Rosela Menurunkan Malondialdehid Pada Tikus Yang Diberi Minyak Jelantah, Tesis, Universitas Udayana, Denpasar.
Usoh I.F, E.J. Akpan, E.O. Etim and E.O. Farombi., 2005, Antioxidant Actions of Dried Flower Extracts of Hibiscus sabdariffa L. On Sodium Arsenite - Induced Oxidative Stress in Rats, Pakistan Journal of Nutrition 4 (3): 135-141, 2005.
Young J, Siming Dong, Qichen Jiang, Tengjiao Kuang, Wenting Huang, Jiaxin Yang., 2013, Changes in Expression of Manganese Superoxide Dismutase, Copper and Zinc Superoxide Dismutase and Catalase in Brachionus calyciflorus during the Aging Process, Plos one Journal, Volume 8.
Wang, C.J., Wang, J.M., Lin, W.L., Chu, C.Y., Chou, F.P., Tseng, T.H., 2000. Protective effect of Hibiscus anthocyanins against tert-butyl hydroperoxide (t-BHT) induced hepatic toxicity in rats. Food and Chemical Toxicology 38, 411–416.
Wijayanti, R., 2013, Efek Ekstrak Etanol Kelopak Bunga Rosela (Hibiscus Sabdariffa L.) Terhadap Penurunan Kadar Gula Darah, Kolesterol, Trigliserida Serta Histopatologi Pankreas Tikus Putih Galur Sprague Dawley Yang diinduksi 7,12 Dimetilbenz(α)Antrasen, Tesis, Universitas Ahmad Dahlan, Yogyakarta.
